February 8, 2011

Chromium Picolinate for Depression?

I have been using Chromium Picolinate for years to help me feel better in the afternoon when I used to always get dizzy and irritated if I didn't eat exactly on time. Here are some relevant studies mentioned on Wikipedia.

From Wikipedia:

It has been noted that patients with atypical depression often suffer from intense cravings for carbohydrates. A mineral supplement, chromium picolinate, was found to assuage these cravings.[5][6] It also was found to have an antidepressant effect on some atypical depression sufferers.[6]

Some hypothesize that atypical depression may be related to thyroid dysregulation. Some studies have found subtle thyroid abnormalities in people with atypical depression.[7] Another study suggests that patients may benefit from triiodothyronine, a medication used to treat hypothyroidism.[8]

References

5. ^ Docherty JP, Sack DA, Roffman M, Finch M, Komorowski JR (September 2005). "A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving". J Psychiatr Pract 11 (5): 302–14. doi:10.1097/00131746-200509000-00004. PMID 16184071.
6. ^ a b Davidson JR, Abraham K, Connor KM, McLeod MN (February 2003). "Effectiveness of chromium in atypical depression: a placebo-controlled trial". Biol. Psychiatry 53 (3): 261–4. doi:10.1016/S0006-3223(02)01500-7. PMID 12559660.
7. ^ http://web.archive.org/web/20070317050218/http://www.webmd.com/depression/news/20040315/atypical-depression-thyroid-link-still-alive Atypical Depression: Thyroid Link Still Alive
8. ^ Iosifescu DV, Nierenberg AA, Mischoulon D, et al. (August 2005). "An open study of triiodothyronine augmentation of selective serotonin reuptake inhibitors in treatment-resistant major depressive disorder". J Clin Psychiatry 66 (8): 1038–42. doi:10.4088/JCP.v66n0812. PMID 16086620. http://article.psychiatrist.com/?ContentType=START&ID=10001405.

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